Conference

Heidelberg Conference on Cancer Neuroscience 2023

1st Heidelberg Conference on Cancer Neuroscience

July 18-19, 2023

Venue: German Cancer Research Center (DKFZ), Communication Center,

Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

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Conference Program

July, 18th 2023
09:00 – 09:30	Welcome and Introduction	Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Wolfgang Wick, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
09:30 – 10:30	INSTRUCTIONS FROM NEURODEVELOPMENT AND THE NORMAL NERVOUS SYSTEM	Chairs: Stefan Pfister, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)), Ana Martin-Villalba, MD, PhD (German Cancer Research Center (DKFZ), Heidelberg)
09:30 – 09:45	Neuron-glial interactions regulating brain development, plasticity and cancer	Michelle Monje, MD, PhD (Stanford University, California)
09:45 – 10:00	Peripheral Nervous System (t.t.)	Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
10:00 – 10:20	Cellular development and evolution of the human brain	Henrik Kaessmann, PhD (Heidelberg University, Medical Faculty)
10:20 – 10:30	Short Talk – Abstract 1
10:30 – 10:45	Coffee Break
10:45 – 12:45	BRAIN CANCER NEUROSCIENCE	Chairs: Thomas Kuner, MD (Heidelberg University, Medical Faculty), Felix Sahm, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
10:45 – 11:05	Paracrine neural influences in gliomagenesis	Michelle Monje, MD, PhD (Stanford University, California)
11:05 – 11:15	Synapses between neurons and glioma cells (t.t.)	Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
11:15 – 11:35	Glioblastoma remodeling of neural circuits in the human brain decreases survival	Shawn Hervey-Jumper, MD (University of California, San Francisco)
11:35 – 11:55	Neuro-glioma crosstalk and glioma invasion (t.t.)	Benjamin Deneen, PhD (Baylor College of Medicine, Housten, Texas)
11:55 – 12:05	Targeting Tumor Microtube-mediated glioblastoma networks	Sophie Weil, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
12:05 – 12:15	Pacemaker-like hub cells in glioblastoma (t.t.)	David Hausmann, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
12:15 – 12:25	Short Talk – Abstract 1
12:25 – 12:35	Short Talk – Abstract 2
12:35 – 12:45	Short Talk – Abstract 3
12:45 – 13:45	Lunch
13:45 – 15:45	EXTRACRANIAL CANCER NEUROSCIENCE	Chairs: Rohini Kuner, PhD (Heidelberg University, Medical Faculty), Erica Sloan, PhD (Monash University, Melbourne)
13:45 – 14:05	Clinical opportunities of translation in extracranial Cancer Neuroscience	Ekin Demir, MD, PhD (TU Munich, Medical Faculty)
14:05 – 14:25	Extracranial cancer neurogenesis (t.t.)	Claire Magnon, PhD (INSERM, Paris)
14:25 – 14:45	Cancer neuroscience: emerging hallmark of cancer	Moran Amit, MD, PhD (MD Anderson, Houston, Texas)
14:45 – 15:05	Molecular targeted therapies for Cancer Neuroscience: learning from general oncology	Sonja Loges, MD, PhD (Heidelberg University, Medical Faculty Mannheim, German Cancer Research Center (DKFZ))
15:05 – 15:15	Single cell atlas of PDAC innervating neurons	Vera Thiel, PhD candidate (German Cancer Research Center (DKFZ), Heidelberg))
15:15 – 15:25	Short Talk – Abstract 1
15:25 – 15:35	Short Talk – Abstract 2
15:35 – 15:45	Short Talk – Abstract 3
15:45 – 16:00	Coffee Break
16:00 – 17:00	METASTASIS CANCER NEUROSCIENCE	Chairs: Humsa Venkatesh, PhD (Harvard University, Boston, Massachusetts), Moran Amit, MD, PhD (MD Anderson, Houston, Texas)
16:00 – 16:20	Neural-Activity Dependent Growth of Brain Metastases	Humsa Venkatesh, PhD (Harvard University, Boston, Massachusetts)
16:20 – 16:40	Neuron-tumor cell synapses drive brain metastases	Matthia Karreman, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
16:40 – 16:50	Short Talk – Abstract 1
16:50 – 17:00	Short Talk – Abstract 2
17:00 – 18:30	NEURO-IMMUNO-ONCOLOGY	Chairs: Lucas Schirmer, MD (Heidelberg University, Medical Faculty Mannheim), Adelheid Cerwenka, PhD (Heidelberg University, Medical Faculty Mannheim)
17:00 – 17:20	Linking a neurodevelopmental disorder to tumor immunity (t.t.)	Douglas Hanahan, PhD (EPFL, Lausanne)
17:20 – 17:40	Nociceptor neuron impact cancer immunosurveillance	Sebastien Talbot, PhD (Queen’s University, Kingston, Ontario)
17:40 – 18:00	Neuron-immune axis support of glioma growth	David Gutmann, MD, PhD (Washington University in St. Louis, Missouri)
18:00 – 18:20	T cell therapy of brain tumors	Michael Platten, MD (Heidelberg University, Medical Faculty Mannheim, German Cancer Research Center (DKFZ))
18:20 – 18:30	Short Talk – Abstract 1
From 19:30	Conference Dinner

July, 19th 2023
09:00 – 10:35	Effects of Cancer and Cancer Therapies on the Nervous System	Chairs: Wolfgang Wick, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)), Christoph Michalski, MD (Ulm University, Heidelberg University, Medical Faculty)
09:00 – 09:15	Neurobiological underpinnings of cancer therapy-related cognitive impairment	Michelle Monje, MD, PhD (Stanford University, California)
09:15 – 09:35	Getting on my nerves: cancer pain	Rohini Kuner, PhD (Heidelberg University, Medical Faculty)
09:35 – 09:55	A psychiatric perspective (t.t.)	Heike Tost, MD, PhD (Heidelberg University, Medical Faculty Mannheim)
09:55 – 10:15	Cancer therapy induced neurodegeneration and neuroprotective strategies	Jorg Dietrich, MD, PhD (Harvard University, Boston, Massachusetts)
10:15 – 10:25	Short Talk – Abstract 1
10:25 – 10:35	Short Talk – Abstract 2
10:35 – 10:45	Coffee Break
10:45 – 11:45	Towards Neuroscience-instructed Cancer Therapies	Chairs: Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)), Sandro Krieg, MD (TU Munich, Heidelberg University, Medical Faculty)
10:45 – 11:05	General considerations & early clinical trials for brain cancer (t.t.)	Wolfgang Wick, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
11:05 – 11:25	Can sympathetic neural signalling be targeted to prevent relapse after cancer treatment?	Erica Sloan, PhD (Monash University, Melbourne)
11:25 – 11:35	Imaging biomarkers of the CNS and PNS	Michael Breckwoldt, MD, PhD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ))
11:35 – 11:45	Short Talk – Abstract 1
11:45 – 12:30	Poster Session 1 (Topics 1-4)
12:30 – 13:15	Lunch
13:15 – 14:45	Technological and Structural Developments for Cancer Neuroscience	Chairs: Sinem Saka, PhD (EMBL, Heidelberg), Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ))
13:15 – 13:35	Deciphering the neuron-tumor cell dialogue with single cell RNA-sequencing	Mariella Filbin, MD, PhD (Harvard University, Boston, Massachusetts)
13:35 – 13:50	Targeted ultrastructure of neuron-tumor interfaces	Thomas Kuner, MD (Heidelberg University, Medical Faculty)
13:50 – 14:05	Recording the physiological history of cells with chemical labeling	Kai Johnsson, PhD (MPI for Medical Research, Heidelberg)
14:05 – 14:15	Region-selective spatial transcriptomics for Cancer Neuroscience	Sinem Saka, PhD (EMBL, Heidelberg)
14:15 – 14:30	Data science & Mathematical modeling	Anna Marciniak-Czochra, PhD (Heidelberg University, Medical Faculty)
14:30 – 14:45	In-vivo imaging approaches for Cancer Neuroscience	Robert Prevedel, PhD (EMBL, Heidelberg)
14:45 – 16:15	Workshops
14:45 – 16:15	How do we advance Cancer Neuroscience?
	A – Technology development	Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Mariella Filbin, MD, PhD (Harvard University, Boston, Massachusetts)
	B – Mathematical modeling and data science	Marciniak-Czochra, PhD (Heidelberg University, Medical Faculty) Judith Zaugg, PhD (EMBL, Heidelberg)
	C – Career development	Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Wolfgang Wick, MD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ))
16:15 – 17:00	Poster Session 2 (Topics 5-8) & Coffee Break
17:00 – 18:00	Panel Discussion
17:00 – 18:00	Where do we stand – what do we need for future development of the field? With Michelle Monje, MD, PhD (Stanford University, California) Douglas Hanahan, PhD (EPFL, Lausanne) Ekin Demir, MD, PhD (TU Munich, Medical Faculty) Sebastien Talbot, PhD (Queen’s University, Kingston, Ontario) Shawn Hervey-Jumper, MD (University of California, San Francisco) Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Wolfgang Wick, MD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ)) Sonja Loges, MD, PhD (Heidelberg University, Medical Faculty Mannheim, German Cancer Research Center (DKFZ))	Moderation Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ))

Heidelberg Conference on Cancer Neuroscience 2023

Conference Program

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