Conference
1st Heidelberg Conference on Cancer Neuroscience
July 18-19, 2023
Venue: German Cancer Research Center (DKFZ), Communication Center,
Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Conference Program
July, 18th 2023 | ||
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09:00 – 09:30 | Welcome and Introduction | Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Wolfgang Wick, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
09:30 – 10:30 | INSTRUCTIONS FROM NEURODEVELOPMENT AND THE NORMAL NERVOUS SYSTEM | Chairs: Stefan Pfister, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)), Ana Martin-Villalba, MD, PhD (German Cancer Research Center (DKFZ), Heidelberg) |
09:30 – 09:45 | Neuron-glial interactions regulating brain development, plasticity and cancer | Michelle Monje, MD, PhD (Stanford University, California) |
09:45 – 10:00 | Peripheral Nervous System (t.t.) | Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
10:00 – 10:20 | Cellular development and evolution of the human brain | Henrik Kaessmann, PhD (Heidelberg University, Medical Faculty) |
10:20 – 10:30 | Short Talk – Abstract 1 | |
10:30 – 10:45 | Coffee Break | |
10:45 – 12:45 | BRAIN CANCER NEUROSCIENCE | Chairs: Thomas Kuner, MD (Heidelberg University, Medical Faculty), Felix Sahm, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
10:45 – 11:05 | Paracrine neural influences in gliomagenesis | Michelle Monje, MD, PhD (Stanford University, California) |
11:05 – 11:15 | Synapses between neurons and glioma cells (t.t.) | Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
11:15 – 11:35 | Glioblastoma remodeling of neural circuits in the human brain decreases survival | Shawn Hervey-Jumper, MD (University of California, San Francisco) |
11:35 – 11:55 | Neuro-glioma crosstalk and glioma invasion (t.t.) | Benjamin Deneen, PhD (Baylor College of Medicine, Housten, Texas) |
11:55 – 12:05 | Targeting Tumor Microtube-mediated glioblastoma networks | Sophie Weil, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
12:05 – 12:15 | Pacemaker-like hub cells in glioblastoma (t.t.) | David Hausmann, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
12:15 – 12:25 | Short Talk – Abstract 1 | |
12:25 – 12:35 | Short Talk – Abstract 2 | |
12:35 – 12:45 | Short Talk – Abstract 3 | |
12:45 – 13:45 | Lunch | |
13:45 – 15:45 | EXTRACRANIAL CANCER NEUROSCIENCE | Chairs: Rohini Kuner, PhD (Heidelberg University, Medical Faculty), Erica Sloan, PhD (Monash University, Melbourne) |
13:45 – 14:05 | Clinical opportunities of translation in extracranial Cancer Neuroscience | Ekin Demir, MD, PhD (TU Munich, Medical Faculty) |
14:05 – 14:25 | Extracranial cancer neurogenesis (t.t.) | Claire Magnon, PhD (INSERM, Paris) |
14:25 – 14:45 | Cancer neuroscience: emerging hallmark of cancer | Moran Amit, MD, PhD (MD Anderson, Houston, Texas) |
14:45 – 15:05 | Molecular targeted therapies for Cancer Neuroscience: learning from general oncology | Sonja Loges, MD, PhD (Heidelberg University, Medical Faculty Mannheim, German Cancer Research Center (DKFZ)) |
15:05 – 15:15 | Single cell atlas of PDAC innervating neurons | Vera Thiel, PhD candidate (German Cancer Research Center (DKFZ), Heidelberg)) |
15:15 – 15:25 | Short Talk – Abstract 1 | |
15:25 – 15:35 | Short Talk – Abstract 2 | |
15:35 – 15:45 | Short Talk – Abstract 3 | |
15:45 – 16:00 | Coffee Break | |
16:00 – 17:00 | METASTASIS CANCER NEUROSCIENCE | Chairs: Humsa Venkatesh, PhD (Harvard University, Boston, Massachusetts), Moran Amit, MD, PhD (MD Anderson, Houston, Texas) |
16:00 – 16:20 | Neural-Activity Dependent Growth of Brain Metastases | Humsa Venkatesh, PhD (Harvard University, Boston, Massachusetts) |
16:20 – 16:40 | Neuron-tumor cell synapses drive brain metastases | Matthia Karreman, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
16:40 – 16:50 | Short Talk – Abstract 1 | |
16:50 – 17:00 | Short Talk – Abstract 2 | |
17:00 – 18:30 | NEURO-IMMUNO-ONCOLOGY | Chairs: Lucas Schirmer, MD (Heidelberg University, Medical Faculty Mannheim), Adelheid Cerwenka, PhD (Heidelberg University, Medical Faculty Mannheim) |
17:00 – 17:20 | Linking a neurodevelopmental disorder to tumor immunity (t.t.) | Douglas Hanahan, PhD (EPFL, Lausanne) |
17:20 – 17:40 | Nociceptor neuron impact cancer immunosurveillance | Sebastien Talbot, PhD (Queen’s University, Kingston, Ontario) |
17:40 – 18:00 | Neuron-immune axis support of glioma growth | David Gutmann, MD, PhD (Washington University in St. Louis, Missouri) |
18:00 – 18:20 | T cell therapy of brain tumors | Michael Platten, MD (Heidelberg University, Medical Faculty Mannheim, German Cancer Research Center (DKFZ)) |
18:20 – 18:30 | Short Talk – Abstract 1 | |
From 19:30 | Conference Dinner |
July, 19th 2023 | ||
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09:00 – 10:35 | Effects of Cancer and Cancer Therapies on the Nervous System | Chairs: Wolfgang Wick, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)), Christoph Michalski, MD (Ulm University, Heidelberg University, Medical Faculty) |
09:00 – 09:15 | Neurobiological underpinnings of cancer therapy-related cognitive impairment | Michelle Monje, MD, PhD (Stanford University, California) |
09:15 – 09:35 | Getting on my nerves: cancer pain | Rohini Kuner, PhD (Heidelberg University, Medical Faculty) |
09:35 – 09:55 | A psychiatric perspective (t.t.) | Heike Tost, MD, PhD (Heidelberg University, Medical Faculty Mannheim) |
09:55 – 10:15 | Cancer therapy induced neurodegeneration and neuroprotective strategies | Jorg Dietrich, MD, PhD (Harvard University, Boston, Massachusetts) |
10:15 – 10:25 | Short Talk – Abstract 1 | |
10:25 – 10:35 | Short Talk – Abstract 2 | |
10:35 – 10:45 | Coffee Break | |
10:45 – 11:45 | Towards Neuroscience-instructed Cancer Therapies | Chairs: Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)), Sandro Krieg, MD (TU Munich, Heidelberg University, Medical Faculty) |
10:45 – 11:05 | General considerations & early clinical trials for brain cancer (t.t.) | Wolfgang Wick, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
11:05 – 11:25 | Can sympathetic neural signalling be targeted to prevent relapse after cancer treatment? | Erica Sloan, PhD (Monash University, Melbourne) |
11:25 – 11:35 | Imaging biomarkers of the CNS and PNS | Michael Breckwoldt, MD, PhD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ)) |
11:35 – 11:45 | Short Talk – Abstract 1 | |
11:45 – 12:30 | Poster Session 1 (Topics 1-4) | |
12:30 – 13:15 | Lunch | |
13:15 – 14:45 | Technological and Structural Developments for Cancer Neuroscience | Chairs: Sinem Saka, PhD (EMBL, Heidelberg), Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) |
13:15 – 13:35 | Deciphering the neuron-tumor cell dialogue with single cell RNA-sequencing | Mariella Filbin, MD, PhD (Harvard University, Boston, Massachusetts) |
13:35 – 13:50 | Targeted ultrastructure of neuron-tumor interfaces | Thomas Kuner, MD (Heidelberg University, Medical Faculty) |
13:50 – 14:05 | Recording the physiological history of cells with chemical labeling | Kai Johnsson, PhD (MPI for Medical Research, Heidelberg) |
14:05 – 14:15 | Region-selective spatial transcriptomics for Cancer Neuroscience | Sinem Saka, PhD (EMBL, Heidelberg) |
14:15 – 14:30 | Data science & Mathematical modeling | Anna Marciniak-Czochra, PhD (Heidelberg University, Medical Faculty) |
14:30 – 14:45 | In-vivo imaging approaches for Cancer Neuroscience | Robert Prevedel, PhD (EMBL, Heidelberg) |
14:45 – 16:15 | Workshops | |
14:45 – 16:15 | How do we advance Cancer Neuroscience? | |
A – Technology development | Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Mariella Filbin, MD, PhD (Harvard University, Boston, Massachusetts) | |
B – Mathematical modeling and data science | Marciniak-Czochra, PhD (Heidelberg University, Medical Faculty) Judith Zaugg, PhD (EMBL, Heidelberg) | |
C – Career development | Frank Winkler, MD (Heidelberg University, Medical Faculty, German Cancer Research Center (DKFZ)) Wolfgang Wick, MD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ)) | |
16:15 – 17:00 | Poster Session 2 (Topics 5-8) & Coffee Break | |
17:00 – 18:00 | Panel Discussion | |
17:00 – 18:00 | Where do we stand – what do we need for future development of the field?
With | Moderation Varun Venkataramani, MD, PhD (Heidelberg University, Medical Faculty), German Cancer Research Center (DKFZ)) |